Public Health
Volume 122, Issue 5 , Pages 516-525 , May 2008

Effect of a community-based delivery of intermittent preventive treatment of malaria in pregnancy on treatment seeking for malaria at health units in Uganda

  • A.K. Mbonye

      Affiliations

    • Department of Community Health, Ministry of Health, Box 7272, Kampala, Uganda
    • Corresponding Author InformationCorresponding author. Tel.: +25677411668.
    • ,
  • K. Schultz Hansen

      Affiliations

    • Department of Health Services Research, Institute of Public Health, University of Aarhus, Aarhus, Denmark
    • ,
  • I.C. Bygbjerg

      Affiliations

    • Institute of Immunology, Microbiology and International Health, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
    • ,
  • P. Magnussen

      Affiliations

    • DBL Centre for Health Research and Development, Institute of Pathobiology, Faculty of Life Sciences, University of Copenhagen, Copenhagen, Denmark

Received 13 November 2006 ,Revised 16 May 2007 ,Accepted 16 July 2007.

References 

  1. Garner P, Gulmezoglu AM. Prevention versus treatment for malaria in pregnant women (Cochrane review). In: The Cochrane Library, Issue 1. Oxford: Update Software; 2001.
  2. Newman RD, Parise ME, Slusker L, Nahlen B, Steketee RW. Safety, efficacy and determinants of effectiveness of antimalarial drugs during pregnancy: implications for prevention programs in Plasmodium falciparum-endemic sub-Saharan Africa. Trop Med Parasitol. 2003;6:488–506
  3. Greenwood B. The use of anti-malarial drugs to prevent malaria in the population of malaria-endemic areas. Am J Trop Med Hyg. 2004;70:1–7
  4. Schultz LJ, Steketee RW, Macheso A, Kazembe P, Chitsulo L, Wirima JJ. The efficacy of antimalarial regimens containing sulphadoxine-pyrimethamine and/or chloroquine in preventing peripheral and placental Plasmodium falciparum among pregnant women in Malawi. Am J Trop Med Hyg. 1995;51:515–522
  5. Shulman CE, Dorman EK, Cutts F, Kawuondo K, Bulmar JN, Peshu N, et al. Intermittent sulphadoxine–pyrimethamine to prevent severe anaemia secondary to malaria in pregnancy a randomized controlled placebo. Lancet. 1999;353:632–636
  6. Rogerson S, Chamhika E, Karijala M, Mkundika P, Mhang C, Molyneux M. Intermittent sulphadoxine–pyrimethamine in pregnancy: effectiveness against malaria morbidity in Blantyre, Malawi in 1997–99. Trans R Soc Trop Med Hyg. 2000;94:549–553
  7. Parise ME, Ayisi JG, Nahlen BL, Schultz LZ, Roberts JM, Misore A, et al. Efficacy of sulphadoxine pyrimethamine for prevention of placental malaria in an area of Kenya with a high prevalence of malaria and human immunodeficiency virus infection. Am J Trop Med Hyg. 1998;59:813–822
  8. van Eijk AM, Ayisi JG, ter Kuile FO, Slutsker L, Otieno JA, Adondi JO, et al. Implementation of intermittent preventive treatment with sulphadoxine–pyrimethamine for control of malaria in pregnancy in Kisumu western Kenya. Trop Med Int Health. 2004;9:630–637
  9. Kayentao K, Kodio M, Newman RD, Magia H, Doumatabe D, Ongoiba A, et al. Comparison of intermittent preventive treatment with chemoprophylaxis for the prevention of malaria during pregnancy in Mali. J Infect Dis. 2005;191:109–116
  10. Uganda Bureau of Statistics. The Uganda demographic and health survey. Entebbe, Uganda: Uganda Bureau of Statistics; 2001;
  11. Ammoti-Kaguna B, Nuwaha F. Factors influencing choice of delivery sites in Rakai district, Uganda. Soc Sci Med. 2000;50:200–213
  12. Ndyomugyenyi R, Neema S, Magnussen P. The use of formal and informal services for antenatal care and malaria treatment in rural Uganda. Health Policy Plann. 1998;13:94–102
  13. Schultz L, Stekette R, Chitsulo L, Macheso A, Nyasulu Y, Ettling M. Malaria and childbearing women in Malawi: knowledge, attitudes and practices. Trop Med Parasitol. 1994;45:65–69
  14. Kengeya JK, Seeley JA, Kajura-Beganja E, Kabunga E, Mubiru E, Sembaja F, et al. Recognition, treatment seeking behaviour and perception of cause of malaria among rural women in Uganda. Acta Trop. 1994;58:267–273
  15. Mbonye AK, Neema S, Magnussen P. Treatment seeking practices for malaria in pregnancy among rural women in Mukono District, Uganda. J Biosoc Sci. 2006;38:221–237
  16. Amuyunzu MK. Wiling the spirits to reveal themselves: rural Kenyan mothers responsibility to restore their children's health. Med Anthropol Q. 1998;12:490–502
  17. Nyamongo IK. Health care switching behaviour of malaria patients in a Kenyan rural community. Soc Sci Med. 2002;54:377–386
  18. Mwenesi HA, Harpharm TT, Snow RW. Child malaria treatment practices among mothers in Kenya. Soc Sci Med. 1995;40:1271–1277
  19. Attanayake N, Fox-Rushby J, Mills A. Household costs of malaria morbidity: a study in Matale district, Sri Lanka. Trop Med Int Health. 2000;5:595–606
  20. Mills A. The consequences of malaria for households: a case study in Nepal. Health Policy. 1994;29:209–227
  21. Walker D, Fox-Rushby J. Economic evaluation of parasitic diseases: a critique of the internal and external validity of published studies. Trop Med Int Health. 2000;5:237–249
  22. Ministry of Health. The health sector strategic plan II, 2005/2010. Kampala, Uganda: Ministry of Health; 2005;
  23. Uganda Bureau of Statistics. The Uganda demographic and health survey; preliminary results. Entebbe, Uganda: Uganda Bureau of Statistics; 2006;
  24. Mbonye AK, Bygbjerg I, Magnussen P. Intermittent preventive treatment of malaria in pregnancy: evaluation of a new delivery approach and the policy implications for malaria control in Uganda. Health Policy. 2006;81:228–241
  25. Ministry of Health. Management of uncomplicated malaria: a practical guide for health workers. 3rd ed. Kampala, Uganda: Ministry of Health; 2005;
  26. Ministry of Health. The malaria in pregnancy control policy. Kampala, Uganda: Ministry of Health; 2001;
  27. Joint Medical Stores. Catalogue and price indicator August. Kampala, Uganda: Colour Press Services Limited; 2003;
  28. Drummond MF, O’Brien B, Stoddart GL, Torrance GW. Methods for the economic evaluation of health care programmes. Oxford: Oxford University Press; 1997;
  29. Conteh L, Walker D. Cost and unit cost calculations using step-down accounting. Health Policy Plan. 2000;19:127–135
  30. Walker D, Kumaranayake L. Allowing for differential timing in cost analyses: discounting and annualization. Health Policy Plan. 2002;17:112–118
  31. Ministry of Health/WHO. Economic burden of malaria in Uganda. Kampala, Uganda: Ministry of Health; 2005;
  32. Brabin BJ. The risks and severity of malaria in pregnant women. Applied field research in Malaria. Report no. 1. Geneva: WHO; 1991.
  33. McGregor IA, Wilson ME, Bilewicz WZ. Malaria infection of the placenta in the Gambia, West Africa, its incidence and relationship to birth weight and placenta weight. Trans R Soc Trop Med Hyg. 1983;93:529–534

PII: S0033-3506(07)00291-0

doi: 10.1016/j.puhe.2007.07.024

Public Health
Volume 122, Issue 5 , Pages 516-525 , May 2008

Article Tools