Public Health
Volume 122, Issue 4 , Pages 417-433, April 2008

Associations between periodontal diseases and systemic diseases: A review of the inter-relationships and interactions with diabetes, respiratory diseases, cardiovascular diseases and osteoporosis

School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA

Received 24 May 2006; received in revised form 30 May 2007; accepted 12 July 2007.

Summary 

The aim of this review article is to examine the associations between periodontal diseases and common systemic diseases, namely diabetes, respiratory diseases, cardiovascular diseases and osteoporosis. A substantial number of review articles have been published to elucidate the relationships between these diseases; however, none provide a complete overview on this topic from the aspects of definition, classification, clinical characteristics and manifestations, inter-relationships and interactions, proposed schematic mechanisms, clinical implications and management of periodontal patients with these systemic diseases. The aim of this article is to provide an overall understanding and general concepts of these issues in a concise and inter-related manner.

Keywords: Periodontal diseases, Systemic diseases, Diabetes, Respiratory diseases, Cardiovascular diseases, Osteoporosis

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PII: S0033-3506(07)00232-6

doi:10.1016/j.puhe.2007.07.004

Public Health
Volume 122, Issue 4 , Pages 417-433, April 2008